Chris Combs, a notable figure from the reality TV show 1000-lb Sisters, has undergone a significant transformation

in his personal health journey. Over the years, he has lost over 150 pounds, motivated by a desire to support his

sisters, Tammy and Amy Slayton, in their own struggles with weight loss. Chris made his reality TV debut alongside

his sisters, but the journey to health started long before the cameras rolled.

Growing up, Chris faced the same obesity challenges that plagued many in his family. Weighing over 450 pounds, he was vulnerable to health issues that often accompany obesity. As the older brother of Amy, Chris’s weight struggles were compounded by the risk factors associated with age. His family’s history of obesity hit close to home when he experienced the tragic loss of his father due to similar health complications. This event served as a wake-up call for Chris, prompting him to reevaluate his lifestyle choices and prioritize his health.

In 2022, Chris became eligible for weight loss surgery and opted for gastric sleeve bypass surgery. This significant step enabled him to shed hundreds of pounds within just a few months. Fast forward to 2025, and Chris has impressively maintained a weight loss of over 150 pounds, showcasing the effectiveness of his commitment to a healthier lifestyle.

At the age of 45, celebrated on October 29, Chris is not only thriving but remains active in the entertainment industry. His popularity surged after he joined 1000-lb Sisters in its second season, where he became a supportive figure for Tammy and Amy. Though he didn’t participate in the show’s inaugural season, Chris quickly became an integral part of the family dynamic on-screen.

In addition to his reality TV endeavors, Chris engages with fans through personalized video messages on platforms like Cameo and Memmo. He also holds a managerial position at McDonald’s, proving that he can maintain his weight loss while working in an environment associated with fast food.

Chris’s endeavors do not stop there; in 2024, he announced his participation in VCC 9 Vet City Con, a horror and pop culture convention that added a new dimension to his career. He maintains a vibrant presence on social media, particularly on Instagram, where he has amassed over 143,000 followers. His posts often feature his family, including his wife, sisters, grandchildren, and friends, highlighting the importance of family in his life.

In January 2025, Chris shared a touching video compilation of cherished moments from a family trip to England, further underscoring the value he places on family experiences. His weight loss journey mirrors that of his sisters, as they have all navigated the challenges of obesity while supporting one another.

Chris’s transformation is not just physical; it’s also motivational. He has completed his first five marathons, a testament to his newfound fitness and determination. Dr. Eric Smith, the surgeon who performed his weight loss surgery, has expressed pride in Chris’s accomplishments, demonstrating that consistency and dedication can yield remarkable results.

As Chris Combs continues to inspire many through his journey, he stands as a beacon of hope for those struggling with similar challenges, proving that it’s never too late to make a change and pursue a healthier, more active life.